Molecule Details
InChIKeyBTIHMVBBUGXLCJ-UHFFFAOYSA-N
Compound Name2-(1-Ethyl-2-hydroxyethylamino)-6-benzylamino-9-isopropylpurine
Canonical SMILESCCC(CO)Nc1nc(NCc2ccccc2)c2ncn(C(C)C)c2n1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)7
Pfam Stratification Homologous
Avg pChEMBL6.62
SourceChEMBL;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P50613 CDK7 Homo sapiens Human PF00069 7.1 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.7 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.3 pIC50 TTD_MultiTarget
P49760 CLK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.3 Ki ChEMBL