Molecule Details
| InChIKey | BTHCJMVMWFFHPR-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-[(2-chloroacetyl)amino]-N-[6-(2-fluoro-3-methoxyphenyl)-1H-indazol-3-yl]benzamide |
| Canonical SMILES | COc1cccc(-c2ccc3c(NC(=O)c4cccc(NC(=O)CCl)c4)n[nH]c3c2)c1F |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.53 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P22455 | FGFR4 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 8.2 | IC50 | ChEMBL;BindingDB |
| P21802 | FGFR2 | Homo sapiens | Human | PF07679 PF13927 PF07714 | 7.8 | IC50 | ChEMBL;BindingDB |
| P22607 | FGFR3 | Homo sapiens | Human | PF21165 PF07679 PF13927 PF07714 | 7.1 | IC50 | ChEMBL;BindingDB |
| P11362 | FGFR1 | Homo sapiens | Human | PF07679 PF00047 PF07714 | 7.0 | IC50 | ChEMBL;BindingDB |