InChIKey	BRZYSWJRSDMWLG-DJWUNRQOSA-N
Compound Name	Geneticin
Canonical SMILES	CN[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H]([C@@H](C)O)[C@@H](O)[C@H](O)[C@H]3N)[C@@H](N)C[C@H]2N)OC[C@]1(C)O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	55
Pfam Stratification	Cross-Family
Avg pChEMBL	8.05
Source	ChEMBL

DrugBank ID	DB04263
Drug Name	Geneticin
CAS Number	49863-47-0
Groups	experimental
ATC Codes	nan
Description	Geneticin (also known as G418) is an aminoglycoside antibiotic similar in structure to gentamicin B1, produced by Micromonospora rhodorangea. Geneticin blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells and is commonly used in laboratory research ...

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Categories: Agents that produce neuromuscular block (indirect) Amebicides Aminoglycoside Antibacterials Anti-Bacterial Agents Anti-Infective Agents Antiparasitic Agents Antiprotozoals Carbohydrates Coccidiostats Glycosides Nephrotoxic agents

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Cross-references: CHEMBL215226 ChemSpider: 110402 C17703 PDB: GET PubChem:123865 PubChem:46505367 Wikipedia: G418 ZINC: ZINC000043543817