N-({4-[(6,7-Dimethoxyquinolin-4-Yl)oxy]phenyl}carbamothioyl)-2-Phenylacetamide

InChIKey	`BRXZUOJFGVQTAB-UHFFFAOYSA-N`
Compound Name	N-({4-[(6,7-Dimethoxyquinolin-4-Yl)oxy]phenyl}carbamothioyl)-2-Phenylacetamide
Canonical SMILES	`COc1cc2nccc(Oc3ccc(NC(=S)NC(=O)Cc4ccccc4)cc3)c2cc1OC`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.65
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P08581	MET	Homo sapiens	Human	PF07714 PF01437 PF01403 PF01833	8.7	pIC50	TTD_MultiTarget
P16234	PDGFRA	Homo sapiens	Human	PF07679 PF25305 PF07714	7.5	IC50	ChEMBL;BindingDB
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	6.7	IC50	ChEMBL;BindingDB