Molecule Details
InChIKeyBQYDGSNDLAZAEW-UHFFFAOYSA-N
Compound Name4-{1H-pyrrolo[2,3-b]pyridin-3-yl}-N-[2-(thiophen-2-yl)ethyl]-1,2,3,6-tetrahydropyridine-1-carboxamide
Canonical SMILESO=C(NCCc1cccs1)N1CC=C(c2c[nH]c3ncccc23)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)13
Pfam Stratification Homologous
Avg pChEMBL6.78
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (13)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.8 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 7.4 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 7.2 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.2 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 7.1 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.9 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.8 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.8 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 6.2 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.0 Ki ChEMBL