Molecule Details
InChIKeyBQWUBCRDJPIJAT-UHFFFAOYSA-N
Compound Name2-({2-[(3-Fluoro-4-methylphenyl)amino]pyrimidin-4-yl}amino)benzoic acid
Canonical SMILESCc1ccc(Nc2nccc(Nc3ccccc3C(=O)O)n2)cc1F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Homologous
Avg pChEMBL7.34
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P49841 GSK3B Homo sapiens Human PF00069 8.5 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 8.3 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 8.2 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 7.8 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.1 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
P11309 PIM1 Homo sapiens Human PF00069 6.8 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.7 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.4 Ki ChEMBL