Molecule Details
InChIKeyBQWBZBFRJHWSEA-UHFFFAOYSA-N
Compound NameN-pyrido[1',2':1,5]pyrazolo[3,4-d]pyrimidin-4-yl-N'-[3-(trifluoromethyl)phenyl]urea
Canonical SMILESO=C(Nc1cccc(C(F)(F)F)c1)Nc1ncnc2nn3ccccc3c12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL6.68
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P49840 GSK3A Homo sapiens Human PF00069 6.8 IC50 ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.8 IC50 ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.6 IC50 ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.6 IC50 ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.6 IC50 ChEMBL