InChIKey	BQJCRHHNABKAKU-KBQPJGBKSA-N
Compound Name	Morphine
Canonical SMILES	CN1CC[C@]23c4c5ccc(O)c4O[C@H]2[C@@H](O)C=C[C@H]3[C@H]1C5
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Homologous
Avg pChEMBL	7.32
Source	ChEMBL;BindingDB

DrugBank ID	DB00295
Drug Name	Morphine
CAS Number	57-27-2
Groups	approved investigational
ATC Codes	A07DA52 N02AA51 N02AA01 N02AG01
Description	Morphine, the main alkaloid of opium, was first obtained from poppy seeds in 1805.[A176035] It is a potent analgesic, though its use is limited due to tolerance, withdrawal, and the risk of abuse.[A176050] Morphine is still routinely used today, though there are a number of semi-synthetic opioids of...

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Categories: Alkaloids Analgesics Anesthetics Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP2C8 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Substrates Heterocyclic Compounds, Fused-Ring High-risk opioids Hypotensive Agents Narcotics Natural Opium Alkaloids Nervous System Neuraxial Anesthetics Opiate Agonists Opiate Alkaloids Opioid Agonist Opioids P-glycoprotein substrates Peripheral Nervous System Agents Phenanthrenes Sensory System Agents Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome UGT1A1 Substrates UGT1A3 substrates UGT2B7 substrates

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Cross-references: BindingDB: 86258 ChEBI: 17303 CHEMBL70 ChemSpider: 4450907 Drugs Product Database (DPD): 9117 C01516 D08233 PDB: MOI PharmGKB: PA450550 PubChem:5288826 PubChem:46505161 RxCUI: 7052 Therapeutic Targets Database: DAP000071 Wikipedia: Morphine ZINC: ZINC000003812983