Molecule Details
InChIKeyBPLTVYXMXOYIBK-DHZHZOJOSA-N
Compound Name2-(2,6-Dichloro-phenylamino)-7-(3-diethylamino-propenyl)-1,6-dimethyl-1,8-dihydro-imidazo[4,5-h]isoquinolin-9-one
Canonical SMILESCCN(CC)C/C=C/c1nc(O)c2c(ccc3nc(Nc4c(Cl)cccc4Cl)n(C)c32)c1C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.86
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 9.7 IC50 ChEMBL
Q06187 BTK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 9.4 IC50 ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 9.2 IC50 ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 8.7 IC50 ChEMBL
O15264 MAPK13 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
P43403 ZAP70 Homo sapiens Human PF07714 PF00017 6.4 IC50 ChEMBL