N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide — MultiTargetDB

Molecule Details

InChIKey	`BOPSUAHGQHFKGG-UHFFFAOYSA-N`
Compound Name	N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide
Canonical SMILES	`Cc1ccc(C(=O)NC2CC2)cc1-c1ccc(C(=O)NCC2CC2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.6
Source	ChEMBL;BindingDB

2D Structure

2D structure

Activity Profile

DrugBank Annotations

DrugBank ID	DB07835
Drug Name	N~3~-cyclopropyl-N~4~'-(cyclopropylmethyl)-6-methylbiphenyl-3,4'-dicarboxamide
CAS Number	nan
Groups	experimental
ATC Codes	nan
Description	nan

Cross-references: BindingDB: 50263093 ChEBI: 90527 CHEMBL478649 ChemSpider: 22377263 PDB: GK5 PubChem:24856363 PubChem:99444306 ZINC: ZINC000003961852

Target Activities (3)

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q16539	MAPK14	Homo sapiens	Human	PF00069	7.9	Ki	ChEMBL;BindingDB
Q15759	MAPK11	Homo sapiens	Human	PF00069	7.6	Ki	ChEMBL;BindingDB
P04792	HSPB1	Homo sapiens	Human	PF00011	7.3	IC50	ChEMBL;BindingDB

DrugBank Target Actions (1)

Target	Gene	Target Name	Action	Type
Q16539	MAPK14	Mitogen-activated protein kinase 14	binder	targets