Molecule Details
InChIKeyBOBGABAXWFYHQX-UHFFFAOYSA-N
Compound Name3-[2-methyl-4-(1-oxo-2,3-dihydro-1H-isoindol-4-yl)phenyl]-1-(3-methylphenyl)urea
Canonical SMILESCc1cccc(NC(=O)Nc2ccc(-c3cccc4c3CNC4=O)cc2C)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.09
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 8.1 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 7.9 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.7 IC50 ChEMBL;BindingDB
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 7.3 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.9 Ki ChEMBL
P42685 FRK Homo sapiens Human PF07714 PF00017 PF00018 6.8 Ki ChEMBL
P29317 EPHA2 Homo sapiens Human PF14575 PF25599 PF01404 PF00041 PF07714 PF00536 6.6 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.5 Ki ChEMBL
P30530 AXL Homo sapiens Human PF00041 PF13927 PF07714 6.0 Ki ChEMBL