Molecule Details
InChIKeyBNVPFDRNGHMRJS-UHFFFAOYSA-N
Compound NameEdicotinib
Canonical SMILESCC1(C)CC=C(c2nc(C3CC(C)(C)OC(C)(C)C3)ccc2NC(=O)c2nc(C#N)c[nH]2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.47
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12504
Drug NameEdicotinib
CAS Number1142363-52-7
Groups investigational
ATC Codes nan
DescriptionJNJ-40346527 has been used in trials studying the treatment of Health and Arthritis, Rheumatoid.

Cross-references: BindingDB: 98634 CHEMBL3674570 ChemSpider: 34951020 PubChem:25230468 PubChem:347828735 Wikipedia: Colony_stimulating_factor_1_receptor
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 8.0 IC50 ChEMBL;BindingDB
P10721 KIT Homo sapiens Human PF00047 PF07714 7.7 IC50 ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.7 IC50 ChEMBL