Molecule Details
InChIKeyBMPSOKZAIFFMLK-LBPRGKRZSA-N
Compound NamePARP7 Inhibitor I-1
Canonical SMILESC[C@@H](CN1CC(C(=O)N2CCN(c3ncc(C(F)(F)F)cn3)CC2)C1)Nc1cn[nH]c(=O)c1C(F)(F)F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Homologous
Avg pChEMBL6.77
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q7Z3E1 TIPARP Homo sapiens Human PF00644 8.1 IC50 ChEMBL
O95271 TNKS Homo sapiens Human PF00023 PF12796 PF00644 PF07647 6.8 IC50 ChEMBL
Q9H2K2 TNKS2 Homo sapiens Human PF00023 PF12796 PF13637 PF00644 PF07647 6.6 IC50 ChEMBL
Q53GL7 PARP10 Homo sapiens Human PF00644 PF23085 6.5 IC50 ChEMBL
Q9H0J9 PARP12 Homo sapiens Human PF00644 PF24356 PF02825 PF23466 PF25261 6.3 IC50 ChEMBL
Q9UGN5 PARP2 Homo sapiens Human PF00644 PF02877 PF05406 6.3 IC50 ChEMBL