Molecule Details
InChIKeyBLTVBQXJFVRPFK-UHFFFAOYSA-N
Compound NameAzd-1080
Canonical SMILESN#Cc1ccc2[nH]c(O)c(-c3ccc(CN4CCOCC4)cn3)c2c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Homologous
Avg pChEMBL6.32
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P49841 GSK3B Homo sapiens Human PF00069 7.5 Ki ChEMBL;BindingDB
Q00535 CDK5 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.3 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.0 Ki ChEMBL