4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-5-pyridin-4-ylmethyl-5H-pyrimido[5,4-b]indole-9-carboxylic acid amide

InChIKey	`BLIMNWSQDQYNMP-UHFFFAOYSA-N`
Compound Name	4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-5-pyridin-4-ylmethyl-5H-pyrimido[5,4-b]indole-9-carboxylic acid amide
Canonical SMILES	`NC(=O)c1cccc2c1c1ncnc(N3CCN(CCc4ccc(F)c(F)c4)CC3)c1n2Cc1ccncc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	6.92
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P33527	ABCC1	Homo sapiens	Human	PF00664 PF00005 PF24357	7.1	IC50	ChEMBL;BindingDB
P08684	CYP3A4	Homo sapiens	Human	PF00067	6.7	IC50	ChEMBL;BindingDB