InChIKey	BKRGVLQUQGGVSM-KBXCAEBGSA-N
Compound Name	Lisuride
Canonical SMILES	CCN(CC)C(=O)N[C@H]1C=C2c3cccc4[nH]cc(c34)C[C@H]2N(C)C1
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	26
Pfam Stratification	Cross-Family
Avg pChEMBL	7.98
Source	BindingDB;ChEMBL;TTD_MultiTarget

DrugBank ID	DB00589
Drug Name	Lisuride
CAS Number	18016-80-3
Groups	approved
ATC Codes	G02CB02 N02CA07
Description	An ergot derivative that acts as an agonist at dopamine D2 receptors (dopamine agonists). It may also act as an antagonist at dopamine D1 receptors, and as an agonist at some serotonin receptors (serotonin agonists).

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Categories: Agents that produce hypertension Alkaloids Analgesics Anti-Dyskinesia Agents Anti-Parkinson Drugs Antidepressive Agents Antimigraine Preparations Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP2D6 Substrates Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 Substrates Dopamine Agents Dopamine Agonists Dopamine Antagonists Ergolines Ergot Alkaloids and Derivatives Ergot-derivative Dopamine Receptor Agonists Genito Urinary System and Sex Hormones Heterocyclic Compounds, Fused-Ring Nervous System Neurotransmitter Agents Prolactine Inhibitors Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin 5-HT1 Receptor Agonists Serotonin 5-HT2 Receptor Antagonists Serotonin Agents Serotonin Receptor Agonists Serotonin Receptor Antagonists

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Cross-references: BindingDB: 50056445 ChEBI: 51164 CHEMBL157138 ChemSpider: 26847 Guide to Pharmacology: 227 IUPHAR: 227 D08132 PDB: H8G PharmGKB: PA164749019 PubChem:28864 PubChem:46505557 RxCUI: 6446 Therapeutic Targets Database: DAP000255 Wikipedia: Lisuride ZINC: ZINC000003831001