Molecule Details
InChIKeyBKDUVKJYBJDZQW-UHFFFAOYSA-N
Compound Name3-(6-Cyclohexylmethoxy-9H-purin-2-ylamino)-benzenesulfonamide
Canonical SMILESNS(=O)(=O)c1cccc(Nc2nc(OCC3CCCCC3)c3nc[nH]c3n2)c1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.65
SourceChEMBL;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB08248
Drug Name3-(6-CYCLOHEXYLMETHOXY-9H-PURIN-2-YLAMINO)-BENZENESULFONAMIDE
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 5550 CHEMBL123368 ChemSpider: 394686 PDB: N76 PubChem:447655 PubChem:99444719 ZINC: ZINC000020149014
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
P06493 CDK1 Homo sapiens Human PF00069 6.7 pIC50 TTD_MultiTarget
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 6.7 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.7 pIC50 TTD_MultiTarget
P78396 CCNA1 Homo sapiens Human PF02984 PF00134 PF16500 6.7 IC50 ChEMBL
O95067 CCNB2 Homo sapiens Human PF02984 PF00134 6.6 IC50 ChEMBL
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 6.6 IC50 ChEMBL
Q8WWL7 CCNB3 Homo sapiens Human PF02984 PF00134 6.6 IC50 ChEMBL
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P20248 CCNA2 Cyclin-A2 binder targets
P24941 CDK2 Cyclin-dependent kinase 2 binder targets