Molecule Details
InChIKeyBKBCSMDCCAWWNC-UHFFFAOYSA-N
Compound Name2-bromo-6-(1-methylindol-3-yl)-5H-pyrrolo[2,3-b]pyrazine
Canonical SMILESCn1cc(-c2cc3nc(Br)cnc3[nH]2)c2ccccc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.5
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
Q00535 CDK5 Homo sapiens Human PF00069 7.2 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 7.0 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P50613 CDK7 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.1 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL