(S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-amine

InChIKey	`BJSFTYZWWXFKSH-FQEVSTJZSA-N`
Compound Name	(S)-1-(6-(furan-3-yl)-5-(3-methyl-1H-pyrazolo[3,4-b]pyridin-5-yl)pyridin-3-yloxy)-3-(1H-indol-3-yl)propan-2-amine
Canonical SMILES	`Cc1n[nH]c2ncc(-c3cc(OC[C@@H](N)Cc4c[nH]c5ccccc45)cnc3-c3ccoc3)cc12`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.43
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P31749	AKT1	Homo sapiens	Human	PF00169 PF00069 PF00433	9.0	IC50	ChEMBL;BindingDB
P08684	CYP3A4	Homo sapiens	Human	PF00067	6.7	IC50	ChEMBL;BindingDB
P49841	GSK3B	Homo sapiens	Human	PF00069	6.6	IC50	ChEMBL;BindingDB