Molecule Details
| InChIKey | BIUDJVBDYHJCCR-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-bromo-6-hydroxy-2-(4-hydroxyphenyl)isoquinolin-1(2H)-one |
| Canonical SMILES | O=c1c2ccc(O)cc2c(Br)cn1-c1ccc(O)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.65 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O95718 | ESRRB | Homo sapiens | Human | PF00104 PF00105 | 7.3 | Ki | BindingDB |
| Q92731 | ESR2 | Homo sapiens | Human | PF12497 PF00104 PF00105 | 7.3 | Ki | ChEMBL;BindingDB |
| P03372 | ESR1 | Homo sapiens | Human | PF12743 PF00104 PF02159 PF00105 | 6.0 | Ki | ChEMBL;BindingDB |
| P11474 | ESRRA | Homo sapiens | Human | PF00104 PF00105 | 6.0 | Ki | ChEMBL;BindingDB |