4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]pyridine — MultiTargetDB

Molecule Details

InChIKey	`BILJSHVAAVZERY-UHFFFAOYSA-N`
Compound Name	4-[3-(4-fluorophenyl)-1H-pyrazol-4-yl]pyridine
Canonical SMILES	`Fc1ccc(-c2n[nH]cc2-c2ccncc2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Homologous
Avg pChEMBL	6.22
Source	ChEMBL;BindingDB

2D Structure

2D structure

Activity Profile

DrugBank Annotations

DrugBank ID	DB07829
Drug Name	4-[3-(4-FLUOROPHENYL)-1H-PYRAZOL-4-YL]PYRIDINE
CAS Number	nan
Groups	experimental
ATC Codes	nan
Description	nan

Cross-references: BindingDB: 19429 CHEMBL1233024 ChemSpider: 10744775 PDB: GG5 PubChem:12106168 PubChem:99444300 ZINC: ZINC000016052350

Target Activities (4)

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O15264	MAPK13	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
P53778	MAPK12	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
Q15759	MAPK11	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
Q16539	MAPK14	Homo sapiens	Human	PF00069	6.2	IC50	ChEMBL;BindingDB

DrugBank Target Actions (1)

Target	Gene	Target Name	Action	Type
Q16539	MAPK14	Mitogen-activated protein kinase 14	inhibitor	targets