Molecule Details
| InChIKey | BIGPXXAUSQLTQR-UHFFFAOYSA-N |
|---|---|
| Compound Name | Hbx-41108 |
| Canonical SMILES | N#Cc1nc2c(nc1C#N)-c1ccc(Cl)cc1C2=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.6 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P40818 | USP8 | Homo sapiens | Human | PF00581 PF00443 PF08969 PF20625 | 7.0 | IC50 | ChEMBL;BindingDB |
| Q96K76 | USP47 | Homo sapiens | Human | PF25985 PF00443 PF19718 | 6.4 | IC50 | ChEMBL |
| Q93009 | USP7 | Homo sapiens | Human | PF22486 PF00443 PF14533 PF12436 | 6.4 | IC50 | ChEMBL;BindingDB |