Molecule Details
| InChIKey | BIEYFOHSWAIQDF-UHFFFAOYSA-N |
|---|---|
| Compound Name | (5-Amino-3-pyridin-3-yl-1,2,4-triazol-1-yl)-(4-methylphenyl)methanone |
| Canonical SMILES | Cc1ccc(C(=O)n2nc(-c3cccnc3)nc2N)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.51 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P49862 | KLK7 | Homo sapiens | Human | PF00089 | 7.4 | IC50 | ChEMBL;BindingDB |
| Q9Y337 | KLK5 | Homo sapiens | Human | PF00089 | 6.6 | IC50 | ChEMBL;BindingDB |
| P00734 | F2 | Homo sapiens | Human | PF00594 PF00051 PF09396 PF00089 | 6.3 | IC50 | ChEMBL;BindingDB |
| Q9Y5Y6 | ST14 | Homo sapiens | Human | PF00431 PF00057 PF01390 PF00089 | 6.2 | IC50 | ChEMBL;BindingDB |
| P00748 | F12 | Homo sapiens | Human | PF00008 PF00039 PF00040 PF00051 PF00089 | 6.1 | IC50 | BindingDB |