Molecule Details
InChIKeyBHKKSKOHRFHHIN-MRVPVSSYSA-N
Canonical SMILESC[C@@H](N)c1cc(Cl)ccc1Cn1c(=S)[nH]c(=O)c2[nH]ccc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.1
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB18963
Drug NameMitiperstat
CAS Number1933460-19-5
Groups investigational
ATC Codes nan
DescriptionMitiperstat is under investigation in clinical trial NCT05492877 (An Efficacy and Safety Study of Mitiperstat (AZD4831) (MPO Inhibitor) vs Placebo in the Treatment of Moderate to Severe COPD.).

Cross-references: BindingDB: 312172 CHEMBL5095218 ChemSpider: 114711423 Wikipedia: Mitiperstat
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P05164 MPO Homo sapiens Human PF03098 8.2 IC50 ChEMBL;BindingDB
P07202 TPO Homo sapiens Human PF03098 PF07645 PF00084 6.0 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P05164 MPO Myeloperoxidase inhibitor targets