Molecule Details
| InChIKey | BGRWSFIQQPVEML-UHFFFAOYSA-N |
|---|---|
| Compound Name | 8-Bromo-1-methyl-6-(2-pyridinyl)-4H-(1,2,4)triazolo(4,3-a)(1,4)benzodiazepine |
| Canonical SMILES | Cc1nnc2n1-c1ccc(Br)cc1C(c1ccccn1)=NC2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.19 |
| Source | ChEMBL |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB14718 |
|---|---|
| Drug Name | Pyrazolam |
| CAS Number | 39243-02-2 |
| Groups | experimental |
| ATC Codes | nan |
| Description | nan |
Categories: Benzazepines Central Nervous System Agents Central Nervous System Depressants GABA Agents GABA Modulators Heterocyclic Compounds, Fused-Ring Hypnotics and Sedatives Illicit Drugs Neurotransmitter Agents
Cross-references: CHEMBL3246831 ChemSpider: 15417688 Wikipedia: Pyrazolam ZINC: ZINC000039247035
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P34903 | GABRA3 | Homo sapiens | Human | PF02931 PF02932 | 8.3 | Ki | ChEMBL |
| P47869 | GABRA2 | Homo sapiens | Human | PF02931 PF02932 | 8.2 | Ki | ChEMBL |
| P18507 | GABRG2 | Homo sapiens | Human | PF02931 PF02932 | 8.2 | Ki | ChEMBL |
| P47870 | GABRB2 | Homo sapiens | Human | PF02931 PF02932 | 8.2 | Ki | ChEMBL |
| P14867 | GABRA1 | Homo sapiens | Human | PF02931 PF02932 | 8.1 | Ki | ChEMBL |
| P31644 | GABRA5 | Homo sapiens | Human | PF02931 PF02932 | 8.1 | Ki | ChEMBL |