Molecule Details
InChIKeyBDXXSFOJPYSYOC-UHFFFAOYSA-N
Compound NamePf-05175157
Canonical SMILESCc1nc2ccc(C(=O)N3CCC4(CC3)CC(=O)c3c(cnn3C(C)C)C4)cc2[nH]1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.36
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12096
Drug NamePF-05175157
CAS Number1301214-47-0
Groups investigational
ATC Codes nan
DescriptionPF-05175157 has been used in trials studying the basic science and treatment of Acne Vulgaris, Diabetes Mellitus, Type 2 Diabetes Mellitus, Diabetes Mellitus Type 2, and Diabetes Mellitus, Type 2, among others.

Cross-references: BindingDB: 50034371 CHEMBL3359265 ChemSpider: 52083240 PubChem:52934180 PubChem:347828400 ZINC: ZINC000117445039
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
O00763 ACACB Homo sapiens Human PF08326 PF21385 PF02785 PF00289 PF00364 PF01039 PF02786 7.4 IC50 ChEMBL;BindingDB
Q13085 ACACA Homo sapiens Human PF08326 PF21385 PF02785 PF00289 PF00364 PF01039 PF02786 7.3 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
O00763 ACACB Acetyl-CoA carboxylase 2 inhibitor targets