Molecule Details
InChIKeyBCZUAADEACICHN-UHFFFAOYSA-N
Compound NameSgx-523
Canonical SMILESCn1cc(-c2ccc3nnc(Sc4ccc5ncccc5c4)n3n2)cn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL7.14
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB06314
Drug NameSGX-523
CAS Number1022150-57-7
Groups investigational
ATC Codes nan
DescriptionA MET receptor tyrosine kinase inhibitor.

Cross-references: BindingDB: 60589 ChEBI: 90624 CHEMBL1236107 ChemSpider: 24608644 PDB: SX8 ZINC: ZINC000039129916
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 8.4 IC50 ChEMBL;BindingDB
P16083 NQO2 Homo sapiens Human PF02525 6.9 Kd ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.1 Kd ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P08581 MET Hepatocyte growth factor receptor inhibitor targets