Molecule Details
InChIKeyBBZSEXSOPOXLIQ-UHFFFAOYSA-N
Compound NameN-[6-chloro-4-(1H-pyrrolo[2,3-b]pyridin-3-yl)pyridin-2-yl]-2,6-difluorobenzamide
Canonical SMILESO=C(Nc1cc(-c2c[nH]c3ncccc23)cc(Cl)n1)c1c(F)cccc1F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Homologous
Avg pChEMBL7.15
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
O00311 CDC7 Homo sapiens Human PF00069 8.6 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.0 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 7.3 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 7.2 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.1 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.4 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.0 Ki ChEMBL