InChIKey	BBAWEDCPNXPBQM-GDEBMMAJSA-N
Compound Name	Telaprevir
Canonical SMILES	CCC[C@H](NC(=O)[C@@H]1[C@H]2CCC[C@H]2CN1C(=O)[C@@H](NC(=O)[C@@H](NC(=O)c1cnccn1)C1CCCCC1)C(C)(C)C)C(=O)C(=O)NC1CC1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	9
Pfam Stratification	Cross-Family
Avg pChEMBL	7.26
Source	BindingDB;ChEMBL

DrugBank ID	DB05521
Drug Name	Telaprevir
CAS Number	402957-28-2
Groups	approved withdrawn
ATC Codes	J05AP02
Description	Telaprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). HCV is a single-stranded RNA virus that is categorized into nine distinct genotypes, with genotype 1 bein...

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Categories: Amino Acids, Peptides, and Proteins Antiinfectives for Systemic Use Antiviral Agents Antivirals for Systemic Use Antivirals for treatment of HCV infections Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strong) Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A5 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Direct Acting Antivirals Enzyme Inhibitors HCV NS3/4A Protease Inhibitors NS3/4A Protease Inhibitors OATP1B1/SLCO1B1 Inhibitors Organic Anion Transporting Polypeptide 1B1 Inhibitors Organic Anion Transporting Polypeptide 2B1 Inhibitors P-glycoprotein inhibitors P-glycoprotein substrates Peptides Protease Inhibitors

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Cross-references: BindingDB: 50326056 ChEBI: 68595 CHEMBL231813 ChemSpider: 2279948 Drugs Product Database (DPD): 20897 D09012 PharmGKB: PA165958354 PubChem:3010818 PubChem:175427024 RxCUI: 1102261 Wikipedia: Telaprevir ZINC: ZINC000003992480