1-methyl-7-[5-(trifluoromethyl)-1H-pyrazol-4-yl]-8,9,10,11-tetrahydro-2H-pyrazolo[4,3-a]phenanthridine-9-carbonitrile

InChIKey	`BALQGRUVODPMAP-UHFFFAOYSA-N`
Compound Name	1-methyl-7-[5-(trifluoromethyl)-1H-pyrazol-4-yl]-8,9,10,11-tetrahydro-2H-pyrazolo[4,3-a]phenanthridine-9-carbonitrile
Canonical SMILES	`Cc1n[nH]c2ccc3nc(-c4c[nH]nc4C(F)(F)F)c4c(c3c12)CCC(C#N)C4`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.93
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	7.8	IC50	ChEMBL;BindingDB
P24941	CDK2	Homo sapiens	Human	PF00069	6.5	IC50	ChEMBL;BindingDB
P78396	CCNA1	Homo sapiens	Human	PF02984 PF00134 PF16500	6.5	IC50	ChEMBL