Molecule Details
| InChIKey | BAFUFNSAYGCZIC-VWLOTQADSA-N |
|---|---|
| Canonical SMILES | C[C@@]1(c2ccc(CCC(=O)O)cc2)C(=O)Nc2nc(-c3nn(CCC(F)(F)C(F)(F)F)c4cc(Cl)ccc34)nc(N)c21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 9.82 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB21683 |
|---|---|
| Drug Name | Frespaciguat |
| CAS Number | 2101645-33-2 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Frespaciguat is a small molecule drug. The usage of the INN stem '-ciguat' in the name indicates that Frespaciguat is a guanylate cyclase activator and stimulator. Frespaciguat is under investigation in clinical trial NCT05612035 (Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and ... |
Cross-references: BindingDB: 280748 CHEMBL5944803