4-((5-((2,2,3,3-tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamoyl)thiazol-4-ylamino)methyl)-N-methylpicolinamide

InChIKey	`BAFNQSRMVYVKQR-UHFFFAOYSA-N`
Compound Name	4-((5-((2,2,3,3-tetrafluoro-2,3-dihydrobenzo[b][1,4]dioxin-6-yl)carbamoyl)thiazol-4-ylamino)methyl)-N-methylpicolinamide
Canonical SMILES	`CNC(=O)c1cc(CNc2ncsc2C(=O)Nc2ccc3c(c2)OC(F)(F)C(F)(F)O3)ccn1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.92
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P10721	KIT	Homo sapiens	Human	PF00047 PF07714	7.9	IC50	ChEMBL;BindingDB
P15056	BRAF	Homo sapiens	Human	PF00130 PF07714 PF02196	7.9	pIC50	TTD_MultiTarget