Molecule Details
| InChIKey | AYTIPFHOSNFHGV-WZUFQYTHSA-N |
|---|---|
| Compound Name | (5Z)-5-(1,3-benzothiazol-6-ylmethylidene)-2-(4,4-dimethyl-2-oxopyrrolidin-3-yl)iminoimidazolidin-4-one |
| Canonical SMILES | CC1(C)CNC(=O)C1NC1=N/C(=C\c2ccc3ncsc3c2)C(=O)N1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.69 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9HAZ1 | CLK4 | Homo sapiens | Human | PF00069 | 7.5 | IC50 | ChEMBL |
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 7.0 | IC50 | ChEMBL |
| Q13627 | DYRK1A | Homo sapiens | Human | PF00069 | 6.8 | IC50 | ChEMBL |
| Q92630 | DYRK2 | Homo sapiens | Human | PF00069 | 6.1 | IC50 | ChEMBL |
| P49760 | CLK2 | Homo sapiens | Human | PF00069 | 6.0 | IC50 | ChEMBL |