AYGHMHFKSMKVAK-INCBEPGWSA-N

InChIKey	`AYGHMHFKSMKVAK-INCBEPGWSA-N`
Canonical SMILES	`COc1ccc(C#N)cc1-c1cc2c(n1C(C)C)C(c1ccc(Cl)cc1)N([C@H]1CC[C@H](O)CC1)C2=O`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	8.6
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P04637	TP53	Homo sapiens	Human	PF00870 PF08563 PF07710 PF18521	8.6	IC50	ChEMBL;BindingDB
Q00987	MDM2	Homo sapiens	Human	PF02201 PF13920 PF00641	8.6	IC50	ChEMBL