Molecule Details
InChIKeyAXXYATYQRMPQSN-QUGAMOGWSA-N
Compound NameFXIa-IN-6
Canonical SMILESCOC(=O)Nc1ccc2c(c1)NC(=O)[C@H](C)CCC[C@H](N1CCC(c3c(F)ccc(Cl)c3F)=CC1=O)c1cc-2ccn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Homologous
Avg pChEMBL8.19
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P03951 F11 Homo sapiens Human PF00024 PF00089 9.6 Ki ChEMBL;BindingDB
P04070 PROC Homo sapiens Human PF14670 PF00594 PF00089 8.7 Ki ChEMBL;BindingDB
P17538 CTRB1 Homo sapiens Human PF00089 7.7 Ki ChEMBL
P40313 CTRL Homo sapiens Human PF00089 7.7 Ki ChEMBL
Q6GPI1 CTRB2 Homo sapiens Human PF00089 7.7 Ki ChEMBL;BindingDB
Q99895 CTRC Homo sapiens Human PF00089 7.7 Ki ChEMBL