Molecule Details
InChIKeyAWSQADBSXFTFKL-UHFFFAOYSA-N
Compound Name6-Bromo-13-thia-2,4,8,12,19-pentaazatricyclo[12.3.1.1~3,7~]nonadeca-1(18),3(19),4,6,14,16-hexaene 13,13-dioxide
Canonical SMILESO=S1(=O)NCCCNc2nc(ncc2Br)Nc2cccc1c2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL7.08
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB08441
Drug Name6-BROMO-13-THIA-2,4,8,12,19-PENTAAZATRICYCLO[12.3.1.1~3,7~]NONADECA-1(18),3(19),4,6,14,16-HEXAENE 13,13-DIOXIDE
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 50400802 CHEMBL1235529 ChemSpider: 8127619 PDB: PY8 PubChem:9952008 PubChem:99444912 ZINC: ZINC000003942821
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P06493 CDK1 Homo sapiens Human PF00069 7.7 IC50 ChEMBL;BindingDB
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.4 IC50 ChEMBL;BindingDB
O14976 GAK Homo sapiens Human PF00069 PF10409 7.0 Kd ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.8 IC50 ChEMBL;BindingDB
P29317 EPHA2 Homo sapiens Human PF14575 PF25599 PF01404 PF00041 PF07714 PF00536 6.5 Kd ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P24941 CDK2 Cyclin-dependent kinase 2 binder targets