Molecule Details
InChIKeyAWJVIOYPZZZYAX-UHFFFAOYSA-N
Compound NameNarmafotinib
Canonical SMILESCOc1cc(C2CCN(C)CC2)ccc1Nc1ncc(C(F)(F)F)c(CCc2ccccc2CC(N)=O)n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.72
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB18463
Drug NameNarmafotinib
CAS Number1393653-34-3
Groups investigational
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 176589 CHEMBL3689071 ChemSpider: 58941272 ZINC: ZINC000147924474
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q05397 PTK2 Homo sapiens Human PF21477 PF00373 PF18038 PF03623 PF07714 9.2 IC50 ChEMBL
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.3 IC50 ChEMBL;BindingDB