4-(4-Bromo-2,3-difluorophenyl)thieno[2,3-c]pyridine-2-carboxamide

InChIKey	`AWJPVXSHMIELNJ-UHFFFAOYSA-N`
Compound Name	4-(4-Bromo-2,3-difluorophenyl)thieno[2,3-c]pyridine-2-carboxamide
Canonical SMILES	`NC(=O)c1cc2c(-c3ccc(Br)c(F)c3F)cncc2s1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	23
Pfam Stratification	Cross-Family
Avg pChEMBL	6.47
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P49841	GSK3B	Homo sapiens	Human	PF00069	8.2	Ki	ChEMBL
P49840	GSK3A	Homo sapiens	Human	PF00069	7.6	Ki	ChEMBL
Q00535	CDK5	Homo sapiens	Human	PF00069	7.3	Ki	ChEMBL
P23443	RPS6KB1	Homo sapiens	Human	PF00069 PF00433	6.8	Ki	ChEMBL
P06493	CDK1	Homo sapiens	Human	PF00069	6.6	Ki	ChEMBL
P11362	FGFR1	Homo sapiens	Human	PF07679 PF00047 PF07714	6.5	Ki	ChEMBL
P17948	FLT1	Homo sapiens	Human	PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854	6.5	Ki	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
Q13627	DYRK1A	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
O96017	CHEK2	Homo sapiens	Human	PF00498 PF00069	6.4	Ki	ChEMBL
Q9HBY8	SGK2	Homo sapiens	Human	PF00069 PF00433	6.4	Ki	ChEMBL
P11309	PIM1	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
Q9P1W9	PIM2	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
P28482	MAPK1	Homo sapiens	Human	PF00069	6.2	Ki	ChEMBL
Q13131	PRKAA1	Homo sapiens	Human	PF16579 PF21147 PF00069	6.2	Ki	ChEMBL
Q5VT25	CDC42BPA	Homo sapiens	Human	PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433	6.2	Ki	ChEMBL
O43293	DAPK3	Homo sapiens	Human	PF00069	6.1	Ki	ChEMBL
P22607	FGFR3	Homo sapiens	Human	PF21165 PF07679 PF13927 PF07714	6.1	Ki	ChEMBL
Q9H4B4	PLK3	Homo sapiens	Human	PF00069 PF00659	6.1	Ki	ChEMBL
O00444	PLK4	Homo sapiens	Human	PF00069 PF18190 PF18409	6.0	Ki	ChEMBL
P45984	MAPK9	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL
P48730	CSNK1D	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL
P51812	RPS6KA3	Homo sapiens	Human	PF00069 PF00433	6.0	Ki	ChEMBL