Molecule Details
| InChIKey | AWJAAKKEYXUCFY-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(2-Ethoxyquinolin-6-yl)-1-((1-methylpiperidin-4-yl)methyl)pyrazolo(3,4-d)pyrimidin-4-amine |
| Canonical SMILES | CCOc1ccc2cc(-c3nn(CC4CCN(C)CC4)c4ncnc(N)c34)ccc2n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.57 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O94806 | PRKD3 | Homo sapiens | Human | PF00130 PF00169 PF00069 PF25525 | 7.4 | IC50 | ChEMBL;BindingDB |
| Q9BZL6 | PRKD2 | Homo sapiens | Human | PF00130 PF00169 PF00069 PF25525 | 7.3 | IC50 | ChEMBL;BindingDB |
| Q15139 | PRKD1 | Homo sapiens | Human | PF00130 PF00169 PF00069 PF25525 | 6.7 | IC50 | ChEMBL;BindingDB |
| A0A0F7UUA6 | Toxoplasma gondii (strain ATCC 50861 / VEG) | Pathogen | PF13499 PF00069 | 8.2 | IC50 | BindingDB | |
| Q9BJF5 | CDPK1 | Toxoplasma gondii | Pathogen | PF13499 PF00069 | 8.2 | IC50 | ChEMBL;BindingDB |