Molecule Details
InChIKeyAVUUHIYJPTWYNX-UHFFFAOYSA-N
Compound NameUS8933228, Ref 2
Canonical SMILESCOCC(=O)Nc1cc(Oc2ccc(NC(=O)Nc3cc(C(C)(C)C)nn3-c3ccc(C)cc3)c3ccccc23)ccn1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.79
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P28223 HTR2A Homo sapiens Human PF00001 8.5 IC50 BindingDB
P08631 HCK Homo sapiens Human PF07714 PF00017 PF00018 8.3 Kd ChEMBL;BindingDB
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 8.3 IC50 ChEMBL;BindingDB
Q9Y4P1 ATG4B Homo sapiens Human PF20166 PF03416 8.3 Kd BindingDB
Q16539 MAPK14 Homo sapiens Human PF00069 7.9 IC50 ChEMBL;BindingDB
P49841 GSK3B Homo sapiens Human PF00069 7.6 Kd ChEMBL;BindingDB
P43405 SYK Homo sapiens Human PF07714 PF00017 7.4 IC50 ChEMBL;BindingDB
P49840 GSK3A Homo sapiens Human PF00069 7.3 IC50 ChEMBL;BindingDB
P53778 MAPK12 Homo sapiens Human PF00069 6.5 IC50 ChEMBL;BindingDB