Molecule Details
InChIKeyAVLYNJZZQYEFEA-XDJHFCHBSA-N
Compound Name2-[(2Z)-2,3-dihydro-1,3-benzothiazol-2-ylidene]-2-(2-{[2-(pyridin-3-yl)ethyl]amino}pyrimidin-4-yl)acetonitrile
Canonical SMILESN#C/C(=C1/Nc2ccccc2S1)c1ccnc(NCCc2cccnc2)n1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)8
Pfam Stratification Homologous
Avg pChEMBL7.0
SourceChEMBL;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q86V86 PIM3 Homo sapiens Human PF00069 7.5 IC50 ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.4 IC50 ChEMBL
P53779 MAPK10 Homo sapiens Human PF00069 7.2 IC50 ChEMBL
P11309 PIM1 Homo sapiens Human PF00069 7.1 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.8 pIC50 TTD_MultiTarget
P45983 MAPK8 Homo sapiens Human PF00069 6.8 IC50 ChEMBL
P45984 MAPK9 Homo sapiens Human PF00069 6.7 IC50 ChEMBL
Q92630 DYRK2 Homo sapiens Human PF00069 6.5 IC50 ChEMBL