InChIKey	AURFZBICLPNKBZ-SYBPFIFISA-N
Compound Name	Allopregnanolone
Canonical SMILES	CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	16
Pfam Stratification	Homologous
Avg pChEMBL	7.66
Source	ChEMBL

DrugBank ID	DB11859
Drug Name	Brexanolone
CAS Number	516-54-1
Groups	approved investigational
ATC Codes	N06AX29
Description	As of March 2019, brexanolone - developed and made available commercially by Sage Therapeutics Inc. as the brand name product Zulresso - is the first drug to have ever been approved by the US FDA specifically for the treatment of postpartum depression (PPD) in adult females [F4066]. Since PPD, like ...

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Categories: Anesthetics Anticonvulsants Antidepressive Agents Carbohydrates Central Nervous System Agents Central Nervous System Depressants Corpus Luteum Hormones Cyclodextrins Dextrins Dietary Carbohydrates Fused-Ring Compounds GABA Agents GABA Modulators Glucans Gonadal Hormones Gonadal Steroid Hormones Hormones Hormones, Hormone Substitutes, and Hormone Antagonists Nervous System Neuroactive Steroid Gamma-Aminobutyric Acid (GABA) A Receptor Positive Modulators Neuroactive Steroid Gamma-Aminobutyric Acid A Receptor Positive Modulator Neurotransmitter Agents Pharmaceutical Preparations Polysaccharides Pregnanes Pregnenediones Pregnenes Progesterone Congeners Psychoanaleptics Starch Steroids

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Cross-references: BindingDB: 50191342 ChEBI: 50169 CHEMBL207538 ChemSpider: 83760 C13712 PDB: Y4B PubChem:92786 PubChem:347828198 RxCUI: 2121777 Wikipedia: Allopregnanolone ZINC: ZINC000004081043