Molecule Details
InChIKeyAUDNGNGLLRZLDR-UHFFFAOYSA-N
Compound Name4-(2-aminoethylamino)-2-(4-methylphenyl)-1H-indole-7-carboxamide
Canonical SMILESCc1ccc(-c2cc3c(NCCN)ccc(C(N)=O)c3[nH]2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)33
Pfam Stratification Cross-Family
Avg pChEMBL6.51
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (33)
Target Gene Organism Category Pfam pChEMBL Type Source
P43405 SYK Homo sapiens Human PF07714 PF00017 7.8 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 7.4 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 7.2 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.9 Ki ChEMBL
P16591 FER Homo sapiens Human PF00611 PF07714 PF00017 6.8 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.8 Ki ChEMBL
Q13131 PRKAA1 Homo sapiens Human PF16579 PF21147 PF00069 6.8 Ki ChEMBL
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 6.8 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.8 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.6 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.6 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.6 Ki ChEMBL
P07949 RET Homo sapiens Human PF00028 PF07714 PF17756 PF17812 PF17813 PF22540 6.5 Ki ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 6.5 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q04912 MST1R Homo sapiens Human PF07714 PF01437 PF01403 PF01833 6.5 Ki ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 6.5 Ki ChEMBL
P10721 KIT Homo sapiens Human PF00047 PF07714 6.4 Ki ChEMBL
Q8IU85 CAMK1D Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 6.4 Ki ChEMBL
P09619 PDGFRB Homo sapiens Human PF00047 PF13927 PF25305 PF07714 6.3 Ki ChEMBL
O14757 CHEK1 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.2 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.1 Ki ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 6.1 Ki ChEMBL
P07948 LYN Homo sapiens Human PF07714 PF00017 PF00018 6.1 Ki ChEMBL
P51812 RPS6KA3 Homo sapiens Human PF00069 PF00433 6.1 Ki ChEMBL
Q02750 MAP2K1 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q05397 PTK2 Homo sapiens Human PF21477 PF00373 PF18038 PF03623 PF07714 6.1 Ki ChEMBL
Q07912 TNK2 Homo sapiens Human PF09027 PF11555 PF07714 PF22931 PF14604 6.1 Ki ChEMBL
O96013 PAK4 Homo sapiens Human PF00786 PF00069 6.0 Ki ChEMBL
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.0 Ki ChEMBL