Molecule Details
InChIKeyATUUNJCZCOMUKD-OKILXGFUSA-N
Compound NameMLi-2
Canonical SMILESC[C@@H]1CN(c2cc(-c3n[nH]c4ccc(OC5(C)CC5)cc34)ncn2)C[C@H](C)O1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL6.72
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
Q5S007 LRRK2 Homo sapiens Human PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477 9.0 IC50 ChEMBL;BindingDB
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.7 IC50 ChEMBL
Q99558 MAP3K14 Homo sapiens Human PF00069 6.6 IC50 ChEMBL
Q99683 MAP3K5 Homo sapiens Human PF19039 PF20309 PF20302 PF13281 PF00069 6.4 IC50 ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.2 IC50 ChEMBL
P41595 HTR2B Homo sapiens Human PF00001 6.1 Ki ChEMBL
P33981 TTK Homo sapiens Human PF00069 6.0 IC50 ChEMBL