Molecule Details
| InChIKey | ATUFTIJKMARLNY-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-[1-(4-Methylsulfonylphenyl)-5-(5,5,8,8-tetramethyl-6,7-dihydronaphthalen-2-yl)pyrazol-3-yl]benzoic acid |
| Canonical SMILES | CC1(C)CCC(C)(C)c2cc(-c3cc(-c4ccc(C(=O)O)cc4)nn3-c3ccc(S(C)(=O)=O)cc3)ccc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.74 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P13631 | RARG | Homo sapiens | Human | PF00104 PF00105 | 9.6 | Ki | ChEMBL |
| P10276 | RARA | Homo sapiens | Human | PF00104 PF00105 | 8.6 | Ki | ChEMBL;BindingDB |
| P19793 | RXRA | Homo sapiens | Human | PF00104 PF11825 PF00105 | 8.6 | Ki | ChEMBL |
| P10826 | RARB | Homo sapiens | Human | PF00104 PF00105 | 8.3 | Ki | ChEMBL |