Molecule Details
| InChIKey | ATJGOPJRRWGHHL-XKZIYDEJSA-N |
|---|---|
| Compound Name | (Z)-5-(3-hydroxybenzylidene)-10-methoxy-2,2,4-trimethyl-2,4a,5,12a-tetrahydro-1H-chromeno[3,4-f]quinolin-9-ol |
| Canonical SMILES | COc1c(O)ccc2c1C1=C(/C(=C/c3cccc(O)c3)O2)C2C(C)=CC(C)(C)NC2C=C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.89 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P04150 | NR3C1 | Homo sapiens | Human | PF02155 PF00104 PF00105 | 8.8 | IC50 | BindingDB |
| P08235 | NR3C2 | Homo sapiens | Human | PF00104 PF00105 | 6.5 | Ki | BindingDB |
| P06401 | PGR | Homo sapiens | Human | PF00104 PF02161 PF00105 | 6.1 | Ki | BindingDB |
| P10275 | AR | Homo sapiens | Human | PF02166 PF00104 PF00105 | 6.0 | Ki | BindingDB |