Molecule Details
InChIKeyASZCABSVZBJTKA-VKUYVZBCSA-N
Compound Name(9S,11E)-12,16-dimethyl-3,7,14,17,23-pentazapentacyclo[13.6.2.12,5.04,9.018,22]tetracosa-1(22),2(24),4,11,15(23),16,18,20-octaen-6-one
Canonical SMILESC/C1=C\C[C@H]2CNC(=O)c3cc([nH]c32)-c2cccc3nc(C)c(nc23)NC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL9.3
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9P1W9 PIM2 Homo sapiens Human PF00069 10.1 IC50 ChEMBL;BindingDB
P11309 PIM1 Homo sapiens Human PF00069 10.0 IC50 ChEMBL;BindingDB
Q86V86 PIM3 Homo sapiens Human PF00069 7.8 IC50 ChEMBL