Molecule Details
| InChIKey | ASRBKZHDORPEHO-KYJIWOQOSA-N |
|---|---|
| Compound Name | Gallinamide A |
| Canonical SMILES | CC[C@H](C)[C@@H](C(=O)O[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)/C=C/C(=O)N1C(=O)C=C(OC)[C@@H]1C)N(C)C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.94 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P07711 | CTSL | Homo sapiens | Human | PF08246 PF00112 | 8.3 | IC50 | ChEMBL;BindingDB |
| P07858 | CTSB | Homo sapiens | Human | PF00112 PF08127 | 7.5 | IC50 | ChEMBL |
| O60911 | CTSV | Homo sapiens | Human | PF08246 PF00112 | 6.6 | IC50 | ChEMBL;BindingDB |
| P25779 | Trypanosoma cruzi | Pathogen | PF12131 PF08246 PF00112 | 9.6 | IC50 | ChEMBL;BindingDB | |
| Q8IIL0 | FP3 | Plasmodium falciparum (isolate 3D7) | Pathogen | PF08246 PF00112 | 7.7 | IC50 | ChEMBL |