Molecule Details
InChIKeyAQZIXHSRFOGYHF-UHFFFAOYSA-N
Compound Name(3-(1H-pyrrolo[2,3-b]pyridin-5-yl)phenyl)(morpholino)methanone
Canonical SMILESO=C(c1cccc(-c2cnc3[nH]ccc3c2)c1)N1CCOCC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL6.37
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.8 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.8 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.5 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.5 Ki ChEMBL
P17948 FLT1 Homo sapiens Human PF07679 PF00047 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 6.4 Ki ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 6.1 Ki ChEMBL
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.1 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.0 Ki ChEMBL