Molecule Details
InChIKeyAQQWWOMMPDCTLW-UHFFFAOYSA-N
Compound Name4-chloro-N-(3-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide
Canonical SMILESO=C(Nc1cnc2[nH]cc(-c3ccccc3)c2c1)c1ccc(Cl)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL6.26
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 6.8 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.7 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P06241 FYN Homo sapiens Human PF07714 PF00017 PF00018 6.2 Ki ChEMBL
P30530 AXL Homo sapiens Human PF00041 PF13927 PF07714 6.2 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.1 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
P42685 FRK Homo sapiens Human PF07714 PF00017 PF00018 6.0 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.0 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.0 Ki ChEMBL